The U.S. Food and Drug Administration has approved doripenem injection, 500 mg intravenous infusion, for the treatment of complicated urinary tract and intra-abdominal infections. Doripenem injection, sold under the trade name Doribax, has been shown to be active against several strains of bacteria.
“This is a significant new drug in the treatment of hospitalized patients with serious bacterial infections,” said Janet Woodcock, M.D., FDA’s deputy commissioner for scientific and medical programs, chief medical officer and acting director, Center for Drug Evaluation and Research.
In several multi-center, multinational studies, doripenem was shown to have a cure rate comparable to the currently prescribed medications levofloxacin, for complicated urinary tract infections, and meropenem, for complicated intra-abdominal infections.
The most common adverse reactions reported were headache, nausea, diarrhea, rash, and phlebitis. In addition, allergic reactions have occurred and some may require immediate treatment.
The safety and effectiveness of doripenem injection in pediatric patients have not been established. Doripenem has not been studied in pregnant women, and the drug should be used during pregnancy only if clearly needed.
Doripenem injection is manufactured by Johnson and Johnson Pharmaceutical Research and Development, LLC, Raritan, N.J.
However it is beneficial to know symptoms of Urinary Tract infections before they become complicated or if one has a clean slate prevent it.
UTI-bladder-Urinary tract infection symptoms:
* Burning sensation when urinating
* Persistent strong urge to urinate
* Going frequently on bathroom passing small amounts of urine
* Strong smelling urine , blood in the urine or cloudy
Prevention of urinary tract infection:
You can take action to prevent urinary tract infection:
* Drink a lot of liquid Cranberry juice(not if you are taking the blood-thinning medication warfarin) and especially water. Cranberry juice is known as good natural remedy for urinary tract infection.
* Urinate promptly, when urge arises. Don't retain urine for a long time after you feel urge to urinate.
* Wipe from front to back after urinating and after bowel movement. It helps bacteria in the anal region from spreading to the vagina and urethra.
* Clean your genital area before sex intercourse
* Empty your bladder as soon as possible after sex intercourse
* Avoid using feminine products that could be potentially irritable, such as deodorant sprays for genital areas.
* Take showers instead of tub baths
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“This is a significant new drug in the treatment of hospitalized patients with serious bacterial infections,” said Janet Woodcock, M.D., FDA’s deputy commissioner for scientific and medical programs, chief medical officer and acting director, Center for Drug Evaluation and Research.
In several multi-center, multinational studies, doripenem was shown to have a cure rate comparable to the currently prescribed medications levofloxacin, for complicated urinary tract infections, and meropenem, for complicated intra-abdominal infections.
The most common adverse reactions reported were headache, nausea, diarrhea, rash, and phlebitis. In addition, allergic reactions have occurred and some may require immediate treatment.
The safety and effectiveness of doripenem injection in pediatric patients have not been established. Doripenem has not been studied in pregnant women, and the drug should be used during pregnancy only if clearly needed.
Doripenem injection is manufactured by Johnson and Johnson Pharmaceutical Research and Development, LLC, Raritan, N.J.
However it is beneficial to know symptoms of Urinary Tract infections before they become complicated or if one has a clean slate prevent it.
UTI-bladder-Urinary tract infection symptoms:
* Burning sensation when urinating
* Persistent strong urge to urinate
* Going frequently on bathroom passing small amounts of urine
* Strong smelling urine , blood in the urine or cloudy
Prevention of urinary tract infection:
You can take action to prevent urinary tract infection:
* Drink a lot of liquid Cranberry juice(not if you are taking the blood-thinning medication warfarin) and especially water. Cranberry juice is known as good natural remedy for urinary tract infection.
* Urinate promptly, when urge arises. Don't retain urine for a long time after you feel urge to urinate.
* Wipe from front to back after urinating and after bowel movement. It helps bacteria in the anal region from spreading to the vagina and urethra.
* Clean your genital area before sex intercourse
* Empty your bladder as soon as possible after sex intercourse
* Avoid using feminine products that could be potentially irritable, such as deodorant sprays for genital areas.
* Take showers instead of tub baths
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